Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression

21 Jul 2011

Abstract excerpt

The carbohydrate response element binding protein (ChREBP), a basic helix-loop-helix/leucine zipper transcription factor, plays a critical role in the control of lipogenesis in the liver. To identify the direct targets of ChREBP on a genome-wide scale and provide more insight into the mechanism by which ChREBP regulates glucose-responsive gene expression, we performed chromatin immunoprecipitation-sequencing and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Lipoproteins and Cardiovascular Health
Share to Plant biochemistry and biosynthesis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21811631
DOI: 10.1371/journal.pone.0022544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene ExpressionPMID 21811631Read ↗

Identification and function of phosphorylation in the glucose-regulated transcription factor ChREBP.Semantic proximity Read ↗

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.Semantic proximity Read ↗

Integration of metabolomic and transcriptomic analyses reveals regulatory functions of the ChREBP transcription factor in energy metabolismSemantic proximity Read ↗

miR-1322 regulates ChREBP expression via binding a 3'-UTR variant (rs1051943).Semantic proximity Read ↗

HGFAC is a ChREBP Regulated Hepatokine that Enhances Glucose and Lipid HomeostasisSemantic proximity Read ↗

HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasisSemantic proximity Read ↗

Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity.Semantic proximity Read ↗

Adaptive and maladaptive roles for ChREBP in the liver and pancreatic islets.Semantic proximity Read ↗

Coordinate regulation/localization of the carbohydrate responsive binding protein (ChREBP) by two nuclear export signal sites: discovery of a new leucine-rich nuclear export signal site.Semantic proximity Read ↗

Genome-Wide Occupancy of SREBP1 and Its Partners NFY and SP1 Reveals Novel Functional Roles and Combinatorial Regulation of Distinct Classes of GenesSemantic proximity Read ↗

Carbohydrate Response Element Binding Protein Gene Expression Is Positively Regulated by Thyroid HormoneSemantic proximity Read ↗

Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.