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Article

Regulation of Hepatic Metabolism and Cell Growth by the ATF/CREB Family of Transcription Factors

15 Feb 2021

Abstract excerpt

The liver is a major metabolic organ that regulates the whole-body metabolic homeostasis and controls hepatocyte proliferation and growth. The ATF/CREB family of transcription factors integrates nutritional and growth signals to the regulation of metabolism and cell growth in the liver, and deregulated ATF/CREB family signaling is implicated in the progression of type 2 diabetes, nonalcoholic fatty liver disease,...

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Share to Endoplasmic Reticulum Stress and Disease
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Identifiers

PMID: 33608424
DOI: 10.2337/dbi20-0006

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