Article

Prognostic role and clinicopathological features of SMAD4 gene mutation in colorectal cancer: a systematic review and meta-analysis

2021-04-09

Abstract excerpt

<h4>Background: </h4> Approximately 5.0%-24.2% of colorectal cancers (CRCs) have activating mutations in SMAD4, making it one of the frequently mutated genes in CRC. We thus carried out a comprehensive system review and meta-analysis investigating the prognostic significance and clinicopathological features of mutation of SMAD4 gene in CRC. <h4>Methods: </h4> A detailed literature search was conducted in PubMed, W...

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Literature Corpus work: f8d9aae3-a9cd-552e-ad61-7dc55a13f1c7
DOI: 10.21203/rs.3.rs-379114/v1

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