Article
SMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene.
BMC cancer - 17 Jun 2010
Sameer A Syed, Chowdri Nissar A, Syeed Nidda, Banday Mujeeb Z, Shah Zaffar A, Siddiqi Mushtaq A
Abstract excerpt
BACKGROUND: The development and progression of colorectal cancer has been extensively studied and the genes responsible have been well characterized. However the correlation between the SMAD4 gene mutations with KRAS mutant status has not been explored by many studies so far. Here, in this study...
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