Article

A novel human monoclonal antibody specific to the A33 glycoprotein recognizes colorectal cancer and inhibits metastasis

2019-08-28

Abstract excerpt

<h4>ABSTRACT</h4> Colorectal cancer represents the second most common cause of cancer-related death. The human A33 transmembrane glycoprotein is a validated tumor-associated antigen, expressed in 95% of primary and metastatic colorectal cancers. Using phage display technology, we generated a human monoclonal antibody (termed A2) specific to A33 and we compared its epitope and performance to those of previously de...

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Literature Corpus work: f7f545a3-2723-5956-bee4-5419d0137303
DOI: 10.1101/748962

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