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Article

Profiling Tumor-Associated Autoantibodies for the Detection of Colon Cancer

1 May 2008

Abstract excerpt

PURPOSE: The purpose of the present study was to screen the autoantibody signature of colon cancers to develop serum markers for colon cancer detection. EXPERIMENTAL DESIGN: A phage cDNA expression library of colon cancer was built. The library was sequentially screened by a pool of 10 colon cancer sera, goat antihuman IgG, and a pool of two healthy sera to identify phage-expressed antigens recognized by...

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PMID: 18451234
DOI: 10.1158/1078-0432.ccr-07-2021

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