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Rational Identification of a Colorectal Cancer Targeting Peptide through Phage Display

8 Mar 2019

Abstract excerpt

Colorectal cancer is frequently diagnosed at an advanced stage due to the absence of early clinical indicators. Hence, the identification of new targeting molecules is crucial for an early detection and development of targeted therapies. This study aimed to identify and characterize novel peptides specific for the colorectal cancer cell line RKO using a phage-displayed peptide library. After four rounds of...

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PMID: 30850705
DOI: 10.1038/s41598-019-40562-1

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