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A Novel Anti-CD44 Variant 9 Monoclonal Antibody C<sub>44</sub>Mab-1 was Developed for Immunohistochemical Analyses Against Colorectal Cancers

2023-03-22

Abstract excerpt

Cluster of differentiation 44 (CD44) is a type I transmembrane glycoprotein, and has been shown as a cell surface marker of cancer stem-like cells in various cancers. Especially, the splicing variants of CD44 (CD44v) are overexpressed in cancers, and play critical roles in cancer stemness, invasiveness, and resistance to chemotherapy and radiotherapy. Therefore, the understanding of the function of each CD44v is i...

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Literature Corpus work
9e9d0276-b882-59c3-b606-bf0d5252b4f0
DOI
10.20944/preprints202303.0399.v1
Open publication

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