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Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic Score

2025-06-22

Abstract excerpt

<h4>Objective</h4> Polygenic scores strongly predict type 1 diabetes risk, but most scores were developed in European-ancestry populations. In this study, we developed a multi-ancestry polygenic score to accurately predict type 1 diabetes risk across diverse populations. <h4>Research Design and Methods</h4> We used recent multi-ancestry genome-wide association studies to create a type 1 diabetes multi-ancestry pol...

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Literature Corpus work
f7d670d2-6cfd-531f-8d10-71f0c4305595
DOI
10.1101/2025.06.20.25329522
Open publication

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Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic ScoreDOI 10.1101/2025.06.20.25329522
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