Article

A murine model of cardiovascular-kidney-metabolic syndrome demonstrates compromised limb function in the ischemic hind limb

2024-12-09

Abstract excerpt

<h4>Abstracts</h4> <h4>Background</h4> Cardiovascular-Kidney-metabolic (CKM) syndrome is a public health problem involving > 90% of the US and results in premature CVD at a relatively preserved GFR. The molecular mediators of CKM are poorly understood, partly due to the lack of a reliable animal model. We set out to generate an animal model with renal and metabolic dysfunctions, using PAD as a CKM manifestation....

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Literature Corpus work: 4cbdd917-4531-53cc-8804-9a6c2174aa2b
DOI: 10.1101/2024.12.03.626707

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