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Article

Super-resolved spatial organization of the nucleolar transcriptome

2026-05-21

Abstract excerpt

<h4>Abstracts</h4> Membraneless organelles (MLOs) often exhibit internal architecture, yet whether the local transcriptome differentially partitions across MLO subdomains remains largely uncharacterized. Here we combine super-resolution imaging with in situ reverse transcription-based sequencing to profile transcriptomes within MLO subdomains. Using the human tripartite nucleolus as a model system, we identify di...

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Literature Corpus work
f76b82ab-e322-5862-81c5-538c58137862
DOI
10.64898/2026.05.19.726041
Open publication

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Super-resolved spatial organization of the nucleolar transcriptomeDOI 10.64898/2026.05.19.726041
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