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snCED-seq: High-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues

2024-10-21

Abstract excerpt

<title>Abstract</title> <p>Profiling cellular heterogeneity in formalin-fixed paraffin-embedded (FFPE) tissues is key to characterizing clinical specimens for biomarkers, therapeutic targets, and drug responses. Recent advancements in single-nucleus RNA sequencing (snRNA-seq) techniques tailored for FFPE tissues have demonstrated their feasibility. However, isolation of high-quality nuclei from FFPE tissue with c...

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Literature Corpus work: 8da67217-317e-55eb-a138-6257ed19b525
DOI: 10.21203/rs.3.rs-5197301/v1

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