Article

Single-Cell Inference of Structural States Of Ribosomes

2026-08-31

Abstract excerpt

Protein synthesis is dynamically regulated to control cell growth, differentiation, and stress responses. Recent single-cell sequencing methods can map ribosome positions on individual transcripts, but cannot capture the global translational states that coordinate protein synthesis across the transcriptome. In contrast, methods that measure the global translational landscape, such as polysome profiling and cryogen...

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Literature Corpus work: e094b001-3e2f-54f4-a826-4b8a4188a320
DOI: 10.64898/2026.08.29.747780

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