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Article

Atlas of Subcellular RNA Localization Revealed by APEX-seq

2018-10-26

Abstract excerpt

<h4>SUMMARY</h4> We introduce APEX-seq, a method for RNA sequencing based on spatial proximity to the peroxidase enzyme APEX2. APEX-seq in nine distinct subcellular locales produced a nanometer-resolution spatial map of the human transcriptome, revealing extensive and exquisite patterns of localization for diverse RNA classes and transcript isoforms. We uncover a radial organization of the nuclear transcriptome,...

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Literature Corpus work
45b22759-c7c0-5b81-8eb0-67354641c1c5
DOI
10.1101/454470
Open publication

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Atlas of Subcellular RNA Localization Revealed by APEX-seqDOI 10.1101/454470
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