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Article

The Nucleolus: In Genome Maintenance and Repair.

International journal of molecular sciences - 1 Jul 2017

Tsekrekou Maria, Stratigi Kalliopi, Chatzinikolaou Georgia

Abstract excerpt

The nucleolus is the subnuclear membrane-less organelle where rRNA is transcribed and processed and ribosomal assembly occurs. During the last 20 years, however, the nucleolus has emerged as a multifunctional organelle, regulating processes that go well beyond its traditional role. Moreover, the unique organization of rDNA in tandem arrays and its unusually high transcription rates make it prone to unscheduled...

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Identifiers

PMID: 28671574
DOI: 10.3390/ijms18071411
PMCID: PMC5535903

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