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CXCL1: A new diagnostic biomarker for human tuberculosis discovered using Diversity Outbred mice

17 Aug 2021

Abstract excerpt

More humans have died of tuberculosis (TB) than any other infectious disease and millions still die each year. Experts advocate for blood-based, serum protein biomarkers to help diagnose TB, which afflicts millions of people in high-burden countries. However, the protein biomarker pipeline is small. Here, we used the Diversity Outbred (DO) mouse population to address this gap, identifying five protein biomarker...

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PMID: 34403447
DOI: 10.1371/journal.ppat.1009773

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