Article

Tuberculosis biomarkers discovered using Diversity Outbred mice

2021-01-09

Abstract excerpt

<h4>Background</h4> Biomarker discovery for pulmonary tuberculosis (TB) may be accelerated by modeling human genotypic diversity and phenotypic responses to Mycobacterium tuberculosis ( Mtb ). To meet these objectives, we use the Diversity Outbred (DO) mouse population and apply novel classifiers to identify informative biomarkers from multidimensional data sets. <h4>Method</h4> To identify biomarkers, we infected...

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Literature Corpus work: 19cd47c7-0a18-5b1e-8083-214c4a236cdb
DOI: 10.1101/2021.01.08.20249024

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