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Article

Characterisation of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

2022-11-29

Abstract excerpt

<h4>Objective</h4> EndoC-βH5 is a newly established human beta-cell model which may be superior to previous models of native human beta cells. Exposure of beta cells to proinflammatory cytokines is a widely used in vitro model of immune-mediated beta-cell failure in type 1 diabetes and we therefore performed an in-depth characterisation of the effects of cytokines on EndoC-βH5 cells. <h4>Methods</h4> The sensiti...

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Literature Corpus work
f6faed81-8ff8-5e0c-801e-ac6d5f1dc05d
DOI
10.1101/2022.11.29.518315
Open publication

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Characterisation of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cellsDOI 10.1101/2022.11.29.518315
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