Article

Stem-Cell-Derived Islets as a Model of Human Islet Inflammation: A Comparative Analysis of Pro-inflammatory Cytokine Responses

2026-05-03

Abstract excerpt

<h4>Background</h4> Inflammation-induced pancreatic islet-cell death and dysfunction are key aspects of both type 1 and type 2 diabetes. Stem cell-derived islets (SC-islets) are an emerging tool in diabetes research, however, our understanding of how inflammation affects SC-islet function is incomplete. We therefore aimed to thoroughly characterize how SC-islets respond to pro-inflammatory cytokines at the functi...

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Literature Corpus work: 8abaaa89-df89-521c-9a78-00fae64c8744
DOI: 10.64898/2026.05.01.722128

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