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Article

Distinct differences in the responses of the human pancreatic β-cell line EndoC-βH1 and human islets to proinflammatory cytokines.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Sept 2015

Oleson Bryndon J, McGraw Jennifer A, Broniowska Katarzyna A, Annamalai Mani, Chen Jing, Bushkofsky Justin R, Davis Dawn B, Corbett John A, Mathews Clayton E

Abstract excerpt

While insulinoma cells have been developed and proven to be extremely useful in studies focused on mechanisms controlling β-cell function and viability, translating findings to human β-cells has proven difficult because of the limited access to human islets and the absence of suitable insulinoma cell lines of human origin. Recently, a human β-cell line, EndoC-βH1, has been derived from human fetal pancreatic...

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Identifiers

PMID: 26084699
DOI: 10.1152/ajpregu.00544.2014
PMCID: PMC4591379

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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