Article

Healthy longevity-associated protein improves cardiac function in murine models of cardiomyopathy with preserved ejection fraction

2024-09-16

Abstract excerpt

<title>Abstract</title> <p>Aims: Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction in ageing and diabetic individuals. In previous studies, a single administration of the longevity-associated variant (LAV) of the human <italic>BPIFB4</italic> gene halted heart d...

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Literature Corpus work: f6c574c8-71a0-501c-a5cf-f82f088e466b
DOI: 10.21203/rs.3.rs-4920130/v1

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