Article

The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice

2023-06-08

Abstract excerpt

<h4>Background: </h4> Cardiac steatosis is an early yet overlooked feature of diabetic cardiomyopathy. There is no available therapy to treat this condition. Tyrosine kinase inhibitors (TKIs), clinically used as an anti-cancer treatment, influence glucose and lipid metabolism, leading to improved glycemic control and allowing insulin discontinuation in cancer patients with diabetes mellitus. The present study aime...

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Literature Corpus work: 4c0855ba-2547-517f-804a-6a2dc1213659
DOI: 10.21203/rs.3.rs-3024470/v1

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