Article

ATX expression from GFAP <sup>+</sup> cells is essential for embryonic development

2020-01-17

Abstract excerpt

Autotaxin (ATX) is secreted by various type of cells in health and disease and catalyzes the extracellular production of lysophosphatidic acid (LPA). In turn, LPA is a bioactive lysophospholipid promoting a wide array of cellular functions through its multiple G-protein coupled receptors, differentially expressed in almost all cell types. ATX expression has been shown necessary for embryonic development and has be...

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Literature Corpus work: f6a0d865-d5d8-5c53-bca6-48b428e843ea
DOI: 10.1101/2020.01.17.910141

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