Article

Conditional <i>Lpar1</i> gene targeting identifies cell types mediating neuropathic pain

2020-02-03

Abstract excerpt

<h4>ABSTRACT</h4> LPA 1 is one of the six known receptors (LPA 1-6 ) for lysophosphatidic acid (LPA). Constitutive Lpar1 null mutant mice have been instrumental in identifying roles for LPA-LPA 1 signaling in neurobiological processes, brain development, and behavior as well as modelling human neurological diseases like neuropathic pain. Constitutive Lpar1 null mutant mice are protected from partial sciatic...

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Literature Corpus work: cf5545a8-a460-5454-bd98-72fbfc48ba57
DOI: 10.1101/2020.02.02.931212

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