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Article

Glial development in the Drosophila CNS requires concomitant activation of glial and repression of neuronal differentiation genes.

Development (Cambridge, England) - 1 Jun 1997

Giesen K, Hummel T, Stollewerk A, Harrison S, Travers A, Klämbt C

Abstract excerpt

Two classes of glial cells are found in the embryonic Drosophila CNS, midline glial cells and lateral glial cells. Midline glial development is triggered by EGF-receptor signalling, whereas lateral glial development is controlled by the gcm gene. Subsequent glial cell differentiation depends partly on the pointed gene. Here we describe a novel component required for all CNS glia development. The tramtrack gene...

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Source

Identifiers

PMID: 9199357
DOI: 10.1242/dev.124.12.2307

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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