Article
Aberrant agouti-related protein system in the hypothalamus of the anx/anx mouse is associated with activation of microglia.
The Journal of comparative neurology - 1 Mar 2008
Nilsson Ida, Lindfors Charlotte, Fetissov Sergueï O, Hökfelt Tomas, Johansen Jeanette E
Abstract excerpt
Agouti-related protein (AgRP) is a key orexigenic neuropeptide expressed in the hypothalamic arcuate nucleus and a marker for neurons conveying hormonal signals of hunger to the brain. Mice homozygous for the anorexia (anx) mutation are characterized by decreased food intake, starvation, and deat...
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