Article

Generation and characterization of <i>Sema6aΔcyt</i> conditional knockout mice

2023-11-06

Abstract excerpt

<h4>ABSTRACT</h4> The axon guidance molecule Semaphorin-6A (SEMA6A) plays a key role during nervous system development. SEMA6A, classically known as a ligand for Plexin-A2 and -A4, is a transmembrane protein that can also elicit signaling via its intracellular domain in vitro . However, the physiological relevance of this ‘ revers e’ signaling route is largely unknown. We generated a new transgenic mouse model,...

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Literature Corpus work: f696fa6f-08cc-5485-aa0e-724bdc05b3ad
DOI: 10.1101/2023.11.06.565851

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