Article

Injury-induced Semaphorin6C/PlexinA2 signaling drives remote neuronal apoptosis and functional impairment in the adult CNS

2026-07-31

Abstract excerpt

<title>Abstract</title> <p> Axonal degeneration is a major driver of disability and disease progression in several central nervous system (CNS) disorders. After injury, neurodegeneration may extend beyond the primary lesion to anatomically and functionally connected neuronal populations, contributing to secondary damage and impaired recovery. Semaphorins are developmental axon guidance molecules that may be reac...

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Literature Corpus work: f5f39250-2a9e-56ef-a4c4-efb947f75896
DOI: 10.21203/rs.3.rs-10267729/v1

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