Article
Bilateral subcortical heterotopia with partial callosal agenesis in a mouse mutant.
Cerebral cortex (New York, N.Y. : 1991) - 1 Apr 2013
Rosen G D, Azoulay N G, Griffin E G, Newbury A, Koganti L, Fujisaki N, Takahashi E, Grant P E, Truong D T, Fitch R H, Lu L, Williams R W
Abstract excerpt
Cognition and behavior depend on the precise placement and interconnection of complex ensembles of neurons in cerebral cortex. Mutations that disrupt migration of immature neurons from the ventricular zone to the cortical plate have provided major insight into mechanisms of brain development and disease. We have discovered a new and highly penetrant spontaneous mutation that leads to large nodular bilateral...
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