Article
The transmembrane Semaphorin Sema I is required in Drosophila for embryonic motor and CNS axon guidance.
Neuron - 1 Feb 1998
Yu H H, Araj H H, Ralls S A, Kolodkin A L
Abstract excerpt
The semaphorins comprise a large family of conserved glycoproteins, several members of which have been shown to function in repulsive neuronal growth cone guidance. We show here that Drosophila Semaphorin I (Sema I), a transmembrane semaphorin expressed on embryonic motor and CNS axons, is requir...
Topics
- Animals
- Axons
- Cell Adhesion Molecules, Neuronal
- Central Nervous System
- Drosophila
- Gene Expression Regulation, Developmental
- Motor Neurons
- Mutation
- Phenotype
- Semaphorins