Article
The transmembrane Semaphorin Sema I is required in Drosophila for embryonic motor and CNS axon guidance.
Neuron - 1 Feb 1998
Yu H H, Araj H H, Ralls S A, Kolodkin A L
Abstract excerpt
The semaphorins comprise a large family of conserved glycoproteins, several members of which have been shown to function in repulsive neuronal growth cone guidance. We show here that Drosophila Semaphorin I (Sema I), a transmembrane semaphorin expressed on embryonic motor and CNS axons, is required for correct guidance of motor axons and for the formation of CNS pathways. In mutant embryos lacking Sema I, motor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.