Article

Cone-shaped HIV-1 capsids are transported through intact nuclear pores

2020-07-30

Abstract excerpt

Human immunodeficiency virus (HIV-1) remains a major health threat. Viral capsid uncoating and nuclear import of the viral genome are critical for productive infection. The size of the HIV-1 capsid is generally believed to exceed the diameter of the nuclear pore complex (NPC), indicating that capsid uncoating has to occur prior to nuclear import. Here, we combined correlative light and electron microscopy with sub...

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Literature Corpus work: f6647859-9759-5fbb-89dc-ba5343fdb033
DOI: 10.1101/2020.07.30.193524

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