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Multiple Roles of HIV-1 Capsid during the Virus Replication Cycle

1 Apr 2019

Abstract excerpt

Human immunodeficiency virus-1 capsid (HIV-1 CA) is involved in different stages of the viral replication cycle. During virion assembly, CA drives the formation of the hexameric lattice in immature viral particles, while in mature virions CA monomers assemble in cone-shaped cores surrounding the viral RNA genome and associated proteins. In addition to its functions in late stages of the viral replication cycle,...

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PMID: 31028522
DOI: 10.1007/s12250-019-00095-3

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