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Neotelomeres and Telomere-Spanning Chromosomal Arm Fusions in Cancer Genomes Revealed by Long-Read Sequencing

2023-12-01

Abstract excerpt

Alterations in the structure and location of telomeres are key events in cancer genome evolution. However, previous genomic approaches, unable to span long telomeric repeat arrays, could not characterize the nature of these alterations. Here, we applied both long-read and short-read genome sequencing to assess telomere repeat-containing structures in cancers and cancer cell lines. Using long-read genome sequences...

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Literature Corpus work
f6566dcf-de07-5a95-98b2-e8cded0de570
DOI
10.1101/2023.11.30.569101
Open publication

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Neotelomeres and Telomere-Spanning Chromosomal Arm Fusions in Cancer Genomes Revealed by Long-Read SequencingDOI 10.1101/2023.11.30.569101
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