Article

Turning the tables: Loss of adaptive immunity reverses sex differences in tuberculosis

2024-09-26

Abstract excerpt

Sex-based differences in innate immunity may play a crucial role in susceptibility to and progression of tuberculosis (TB), a disease that disproportionately affects men. This study aimed to examine whether early host-pathogen interactions contribute to the heightened vulnerability of males to Mycobacterium tuberculosis ( Mtb ) infection. Using recombination activating gene knockout (RAG KO) mice, which lack ada...

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Identifiers and source

Literature Corpus work: f64d5c01-b783-5951-bfef-32154f566939
DOI: 10.1101/2024.09.24.614709

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