Article
Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells.
Journal of immunology research - 1 Jan 2015
Sia Jonathan Kevin, Georgieva Maria, Rengarajan Jyothi
Abstract excerpt
Tuberculosis (TB) remains a serious global public health problem that results in up to 2 million deaths each year. TB is caused by the human pathogen, Mycobacterium tuberculosis (Mtb), which infects primarily innate immune cells patrolling the lung. Innate immune cells serve as barometers of the immune response against Mtb infection by determining the inflammatory milieu in the lungs and promoting the generation...
Topics
- Disease Susceptibility
- Genetic Predisposition to Disease
- Humans
- Immune System
- Immunity, Innate
- Immunologic Surveillance
- Immunomodulation
- Mycobacterium tuberculosis
- Tuberculosis
