Article

Longitudinal multi-omic profiling of a pig-to-human lung xenograft reveals phased immune and tissue-remodeling responses

2026-08-11

Abstract excerpt

<title>Abstract</title> <p>A prior clinical study showed that six-gene-edited pig lung xenografts transplanted into human decedents restricted hyperacute rejection and remained functional for nine days. To define the accompanying molecular landscape, we integrated longitudinal bronchoalveolar lavage fluid (BALF) EV-enriched proteomics, Peripheral Blood Mononuclear Cells (PBMC) CyTOF profiling and spatial transcri...

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Literature Corpus work: f6136dfd-c8a3-56c1-b6a0-f31f5bd30760
DOI: 10.21203/rs.3.rs-10351832/v1

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Longitudinal multi-omic profiling of a pig-to-human lung xenograft reveals phased immune and tissue-remodeling responsesDOI 10.21203/rs.3.rs-10351832/v1Read

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