Article

Integrative Multi-omic Profiling of Two Human Decedents Receiving Pig Heart Xenografts Reveals Strong Perturbations in Early Immune-Cell and Cellular Metabolism Responses

2023-06-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Recent advances in xenotransplantation in living and decedent humans using pig xenografts have laid promising groundwork towards future emergency use and first in human trials. Major obstacles remain though, including a lack of knowledge of the genetic incompatibilities between pig donors and human recipients which may led to harmful immune responses against the xenograft or...

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Literature Corpus work: f20ebc3e-a194-5599-bae9-f38f1bf6b390
DOI: 10.1101/2023.06.05.543406

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