Article

Spatiotemporal immune atlas of the first clinical-grade, gene-edited pig-to-human kidney xenotransplant

2023-01-09

Abstract excerpt

<title>Abstract</title> <p>Pig-to-human xenotransplantation is rapidly approaching the clinical arena; however, it is unclear which immunomodulatory regimens will effectively control human immune responses to pig xenografts. We transplanted a gene-edited pig kidney into a brain-dead human recipient on pharmacologic immunosuppression and studied the human immune response to the xenograft using spatial transcriptom...

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Literature Corpus work: 9e381268-84e6-5e84-a7e9-ce062dcbd4ba
DOI: 10.21203/rs.3.rs-2382345/v1

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