Article

Reduced endothelial activation upon human blood perfusion of pig kidney xenografts lacking MHC class I and three xenoantigens

2022-01-05

Abstract excerpt

<title>Abstract</title> <p>Genetically tailored pigs to eliminate human immune rejection of xenografts is one promising solution to the global donor organ shortage. The development of xenograft transplantation has however been hampered by incomplete understanding of its immune rejection and the inability to test this in a human transplantation setting. Here we use an ex vivo organ perfusion system with human whol...

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Literature Corpus work: 86561b82-9798-54fb-ae5d-cd1439e5b089
DOI: 10.21203/rs.3.rs-1146675/v1

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Reduced endothelial activation upon human blood perfusion of pig kidney xenografts lacking MHC class I and three xenoantigensDOI 10.21203/rs.3.rs-1146675/v1Read

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