Article
The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem
2016-05-10
Abstract excerpt
Several important and fundamental aspects of disease genetics models have yet to be described. One such property is the relationship of disease association statistics at a marker site closely linked to a disease causing site. A complete description of this two-locus system is of particular importance to experimental efforts to fine map association signals for complex diseases. Here, we present a simple relationshi...
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Identifiers and source
- Literature Corpus work
- f609755b-3750-5e7b-864e-04f6ff0b509a
- DOI
- 10.1101/052381