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Article

The Role of Inflammasomes in Glomerulonephritis

11 Apr 2022

Abstract excerpt

The inflammasome is an immune multiprotein complex that activates pro-caspase 1 in response to inflammation-inducing stimuli and it leads to IL-1β and IL-18 proinflammatory cytokine production. NLRP1 and NLRP3 inflammasomes are the best characterized and they have been related to several autoimmune diseases. It is well known that the kidney expresses inflammasome genes, which can influence the development of some...

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PMID: 35457026
DOI: 10.3390/ijms23084208

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