Article
The Roles of Kidney-Resident ILC2 in Renal Inflammation and Fibrosis.
Frontiers in immunology - 1 Jan 2021
Nagashima Ryuichi, Iyoda Masayuki
Abstract excerpt
Innate lymphoid cells (ILCs) are a recently discovered lymphocyte population with high cytokine productive capacity. Type-2 ILCs (ILC2s) are the most studied, and they exert a rapid type-2 immune response to eliminate helminth infections. Massive and sustainable ILC2 activation induces allergic tissue inflammation, so it is important to maintain correct ILC2 activity for immune homeostasis. The ILC2-activating...
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