Article

Patient-derived tumor explant models of tumor immune microenvironment reveal distinct and reproducible immunotherapy responses

2024-05-14

Abstract excerpt

<h4>ABSTRACT</h4> Tumor-resident immune cells play a crucial role in eliciting anti-tumor immunity and immunomodulatory drug responses, yet these functions have been difficult to study without tractable models of tumor immune microenvironment (TIME). Patient-derived ex vivo models contain authentic resident immune cells and therefore, could provide new mechanistic insights into how TIME responds to tumor or immu...

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Literature Corpus work: f5a4d725-504a-531d-822e-38cc30c365ee
DOI: 10.1101/2024.05.11.593502

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