Article

Engineering the Immune Microenvironment into Organoid Models

2023-01-17

Abstract excerpt

Organoid models have revolutionized cancer research through their ability to capture the cellular heterogeneity and spatial organization of a tumor in 3D culture. Patient-derived organoids can also mirror responses to therapy in vitro, opening the doors to personalized medicine that can direct clinical decision-making. As cancer immunotherapy has flourished and efforts to develop novel immunotherapies have increas...

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Literature Corpus work: 39b0cccd-acad-56db-ab9a-1da089bc29f9
DOI: 10.1146/annurev-cancerbio-061421-040659

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