Article

Spatial immune hubs defined by conserved activated dendritic cells are remodeled by immunotherapy

2026-02-11

Abstract excerpt

<h4>ABSTRACT</h4> Dendritic cells (DCs) orchestrate anti-tumor immune responses, yet the full extent of their phenotypic diversity, and spatial dynamics within the tumor microenvironment (TME) remains incompletely understood. Here, we constructed an integrated atlas of tumor-infiltrating DCs by harmonizing single-cell transcriptomic data from 12 murine tumor studies and 28 published human cancer datasets, togethe...

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Literature Corpus work: eac20210-b28b-5803-8b05-b05123962817
DOI: 10.64898/2026.02.10.703136

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