Article

Dynamic activity of <i>Erg</i> promotes aging of the hematopoietic system

2025-01-23

Abstract excerpt

<h4>ABSTRACT</h4> Hematopoiesis changes to adapt to the physiology of development and aging. Temporal changes in hematopoiesis parallel age-dependent incidences of blood diseases. Several heterochronic regulators of hematopoiesis have been identified, but how the master transcription factor (TF) circuitry of definitive hematopoietic stem cells (HSCs) adapts over the lifespan is unknown. Here, we show that express...

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Literature Corpus work: f59e1b98-2790-55b1-b4e0-7a399c15908b
DOI: 10.1101/2025.01.23.634563

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