Article

Hematopoiesis at single cell resolution spanning human development and maturation

2021-08-25

Abstract excerpt

Hematopoiesis is a process of constitutive regeneration whereby hematopoietic stem and progenitor cells (HSPCs) replenish mature blood cells. During maturation and aging, HSPCs shift their output to support the demands of prenatal development and postnatal maturation both at homeostasis and in response to stress. How HSPC ontogeny changes throughout life is unknown; studies to date have largely focused on specific...

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Literature Corpus work: 5da40cb9-89f7-59cd-ad56-fde699786ce6
DOI: 10.1101/2021.08.25.457678

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