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<i>ERG</i> Is a Megakaryocytic Oncogene

1 Jun 2009

Abstract excerpt

Ets-related gene (ERG) is a member of the ETS transcription factor gene family located on Hsa21. ERG is known to have a crucial role in establishing definitive hematopoiesis and is required for normal megakaryopoiesis. Truncated forms of ERG are associated with multiple cancers such as Ewing's sarcoma, prostate cancer, and leukemia as part of oncogenic fusion translocations. Increased expression of ERG is highly...

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PMID: 19487285
DOI: 10.1158/0008-5472.can-09-0075

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<i>ERG</i> Is a Megakaryocytic OncogenePMID 19487285Read ↗

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