Article
Epistasis Analysis: Classification Through Machine Learning Methods.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Liu Linjing, Wong Ka-Chun
Abstract excerpt
Complex disease is different from Mendelian disorders. Its development usually involves the interaction of multiple genes or the interaction between genes and the environment (i.e. epistasis). Although the high-throughput sequencing technologies for complex diseases have produced a large amount of data, it is extremely difficult to analyze the data due to the high feature dimension and the combination in the...
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