Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of Apolipoprotein E Variants: A Review of Naturally Occurring Variants and Clinical Features

7 Jan 2025

Abstract excerpt

Apolipoprotein E (apoE) is a key apoprotein in lipid transport and is susceptible to genetic mutations. ApoE variants have been studied for four decades and more than a hundred of them have been reported. This paper presents an up-to-date review of the function and structure of apoE in lipid metabolism, the E2, E3, and E4 isoforms, the APOE gene, and various pathologies, such as familial type III hyperlipidemia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes, Cardiovascular Risks, and Lipoproteins
Share to HIV-related health complications and treatments
Share to Lipoproteins and Cardiovascular Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39779225
DOI: 10.5551/jat.65393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of Apolipoprotein E Variants: A Review of Naturally Occurring Variants and Clinical FeaturesPMID 39779225Read ↗

Apolipoprotein E: far more than a lipid transport protein.Semantic proximity Read ↗

Apolipoprotein ESemantic proximity Read ↗

Beyond the CNS: The many peripheral roles of APOE.Semantic proximity Read ↗

The role of apolipoprotein E genetic variants in lipoprotein disorders.Semantic proximity Read ↗

Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels.Semantic proximity Read ↗

Evolution of human apolipoprotein E (APOE) isoforms: Gene structure, protein function and interaction with dietary factors.Semantic proximity Read ↗

Mechanisms linking apolipoprotein E isoforms with cardiovascular and neurological diseasesSemantic proximity Read ↗

ApoE in Alzheimer's disease: pathophysiology and therapeutic strategies.Semantic proximity Read ↗

ApoE genotype: from geographic distribution to function and responsiveness to dietary factors.Semantic proximity Read ↗

Apolipoprotein E4: an allele associated with many diseases.Semantic proximity Read ↗

Functional diversity of apolipoprotein E: from subcellular localization to mitochondrial functionSemantic proximity Read ↗

The Impact of the Apolipoprotein E Genotype on Cardiovascular Disease and Cognitive Disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.